𝘕,𝘕'-Diisopropyl-𝙊-𝙩𝙚𝙧𝙩-butyl isourea: an efficient reagent for 𝙩𝙚𝙧𝙩-butyl esters synthesis

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Beschreibung

tert-Butyl esters are commonly used as protecting group of carboxylic acids in multi-step synthesis, especially with amino acids, peptides and natural products. [1] The importance of this relatively hindered protecting group is well established.

Organic Syntheses Procedure

Enantioselective Total Syntheses of Cyathane Diterpenoids - Nakada - 2014 - The Chemical Record - Wiley Online Library

Organic Syntheses Procedure

tert-Butyl Nitrite 540-80-7 Tokyo Chemical Industry UK Ltd.

Synthesis of 3(2H)‐Furanones: A Review - Omanakuttan - 2021 - European Journal of Organic Chemistry - Wiley Online Library

An efficient synthesis of α-deuterated carboxylic acids

tert-Butylethylcarbodiimide as an Efficient Substitute for Diisopropylcarbodiimide in Solid-Phase Peptide Synthesis: Understanding the Side Reaction of Carbodiimides with OxymaPure

Outline syntheses of each of the following from acetoacetic ester and any other required reagents: a. tert-butyl methyl ketone b. 2-hexanone c. 2,5-hexanedione d. 4-hydroxypentanoic acid e. 2-ethyl-1

Full article: Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis

An efficient synthesis of α-deuterated carboxylic acids