Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain

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Beschreibung

Peroxynitrite (ONOO-) plays a critical role in Alzheimer's disease (AD), and the association between ONOO- and AD is inexplicit. To reveal the ONOO- influxes in AD brains, an activatable activity-based fluorescence probe Rd-DPA3 was rationally designed by a structure-modulated strategy. Taking advantage of ONOO--sparked two-step cascade reactions of a novel chemical trigger, Rd-DPA3 specifica

Activatable Near-Infrared Fluorescent and Photoacoustic Dual-Modal

An efficient TP-FRET-based lysosome-targetable fluorescent probe

An Activity‐Based Fluorescent Probe for Imaging Fluctuations of

An Activity‐Based Fluorescent Probe for Imaging Fluctuations of

Imaging of ONOO À in live cells (A) RAW 264.7 cells only (a

Investigating New Applications of a Photoswitchable Fluorescent

Molecules, Free Full-Text

An Activity‐Based Fluorescent Probe for Imaging Fluctuations of

An Activity‐Based Fluorescent Probe for Imaging Fluctuations of