The cryo-EM structure of the human neurofibromin dimer reveals the
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41594-021-00687-2/MediaObjects/41594_2021_687_Fig1_HTML.png)
![](https://www.ebi.ac.uk/emdb/images/entry/EMD-13391/400_13391.gif)
EMDB < EMD-13391
![](https://www.scimex.org/__data/assets/image/0009/765369/thumbnail_NF1.jpg)
Structure of common tumour-causing protein found - Scimex
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs42003-023-04815-0/MediaObjects/42003_2023_4815_Fig3_HTML.png)
The therapeutic potential of neurofibromin signaling pathways and binding partners
![](https://www.ebi.ac.uk/pdbe/static/entry/7mp5_deposited_chain_front_image-200x200.png)
PDB 7mp5 structure summary ‹ Protein Data Bank in Europe (PDBe) ‹ EMBL-EBI
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41594-021-00687-2/MediaObjects/41594_2021_687_Fig4_HTML.png)
The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs42003-023-04815-0/MediaObjects/42003_2023_4815_Fig4_HTML.png)
The therapeutic potential of neurofibromin signaling pathways and binding partners
![](https://cdn.rcsb.org/images/structures/7pgt_model-1.jpeg)
RCSB PDB - 7PGT: The structure of human neurofibromin isoform 2 in opened conformation.
![](https://ars.els-cdn.com/content/image/1-s2.0-S0021925817499194-gr7.jpg)
Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer - ScienceDirect
![](https://www.mdpi.com/ijms/ijms-23-05707/article_deploy/html/images/ijms-23-05707-g004.png)
IJMS, Free Full-Text